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WHY THIS MATTERS IN BRIEF

As we manufacture products in new ways we can use those same manufacturing technologies to embed information about them for a variety of purposes.

 

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Now that we can 3D print objects researchers are doing their best to figure out what else they could do with the technology to help improve things in the future, and now one team has come up with the idea of being able to use DNA to embed information that “lasts forever” into the objects they print – which could have a variety of uses that include helping future civilisations understand more about today’s world, all the way through to being able to keep information about an objects provenance with it forever. And more.

 

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Last week a team 3D printed a polyester rabbit embedded with DNA that contains a blueprint for printing additional bunnies, and using the information researchers have replicated the rabbit several times, highlighting the potential for using DNA to store information in everyday objects. Now, I know what you’re thinking – what’s the point? But in some situations this would be useful.

 

Learn more about the technology
 

The plastic bunny was developed by the teams of Robert Grass at the Swiss Federal Institute of Technology in Zurich and Yaniv Erlich at Erlich Lab, a DNA storage company in Israel. “One day he [Erlich] wrote an email – ‘Hey, what if we put real information into your object? That would be really cool,’” says Grass.

The four DNA bases –Adenine (A), Cytosine (C), Thymine (T) and Guanine (G) – were used to encode the 45 kilobyte instructions for making the bunny and the corresponding DNA sequence was then synthesised. The DNA was first packaged into microscopic spheres of glass to protect it, before being incorporated into the plastic that formed the bunny.

 

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The teams then put their 3D printed bunny to the test by cutting off a piece of plastic from its ear and isolating the embedded DNA. They used a DNA sequencing machine to read the specific sequence of DNA bases, which was then translated into instructions for the 3D printer.

The 3D printer then produced a second, identical, plastic bunny, complete with DNA-containing glass spheres. The teams then used this second bunny to produce a third. They repeated this replication process four times in total. Replication was still possible after one of the bunnies had been stored for nine months.

“We were extremely happy once we could read our first bunnies,” says Grass. He says his next goal is to make DNA storage an everyday technology.

“The creativity of this embryonic field just keeps getting better,” says George Church at Harvard University. Church says the creation of a functional object with DNA memory is a “big step”. DNA storage could have future applications in manufacturing, where instructions could be stored locally in objects.

 

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“You can imagine a system where everything is tagged with small bits of useful information,” says Sriram Kosuri at the University of California, Los Angeles. “What’s cool about this work is that they show that is doable today, and it seems pretty reliable,” says Kosuri.

“Any potential application is still likely years away, but this study is certain to inspire creative uses we can’t predict right now,” says Calin Plesa at the University of Oregon. It is interesting to think of a possible distant future where archaeologists use the DNA embedded in human-made artefacts to learn more about our civilisation, says Plesa.

Journal reference: Nature Biotechnology, DOI: 10.1038/s41587-019-0356-z

About author

Matthew Griffin

Matthew Griffin, described as “The Adviser behind the Advisers” and a “Young Kurzweil,” is the founder and CEO of the World Futures Forum and the 311 Institute, a global Futures and Deep Futures consultancy working between the dates of 2020 to 2070, and is an award winning futurist, and author of “Codex of the Future” series. Regularly featured in the global media, including AP, BBC, CNBC, Discovery, RT, and Viacom, Matthew’s ability to identify, track, and explain the impacts of hundreds of revolutionary emerging technologies on global culture, industry and society, is unparalleled. Recognised for the past six years as one of the world’s foremost futurists, innovation and strategy experts Matthew is an international speaker who helps governments, investors, multi-nationals and regulators around the world envision, build and lead an inclusive, sustainable future. A rare talent Matthew’s recent work includes mentoring Lunar XPrize teams, re-envisioning global education and training with the G20, and helping the world’s largest organisations envision and ideate the future of their products and services, industries, and countries. Matthew's clients include three Prime Ministers and several governments, including the G7, Accenture, Bain & Co, BCG, Credit Suisse, Dell EMC, Dentons, Deloitte, E&Y, GEMS, Huawei, JPMorgan Chase, KPMG, Lego, McKinsey, PWC, Qualcomm, SAP, Samsung, Sopra Steria, T-Mobile, and many more.

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